Nigeria, Senegal, Ghana, and the holders Algeria started the group stage qualifiers with back-to-back victories.
Tunisia (1-0 winners in Equatorial Guinea), and Madagascar, who won 6-2 in Niger, added their names to that list with wins on the 19th November.
And the competition has now been moved back to January due to weather concerns during the Cameroon summer.
Six out of the eight knockout places are now assigned after Wydad, Raja Casablanca, Zamalek and the holders Esperance joined TP Mazembe and Mamelodi Sundowns in the final stages.
Al-Ahly, Al-Hilal (Sudan) and Etoile du Sahel will battle it out in Group B for the two remaining slots.
Following the knockout draw, the odds favour Manchester City (despite being drawn against record winners Real Madrid), Liverpool (who meet Atletico), Barcelona (who face Napoli), and PSG, who are matched with Borussia Dortmund.
Those games begin in the middle of February.
Chelsea, Leicester, Sheffield United and Norwich all won through to the next round of the FA Cup.
But troubled West Ham lost at home to Championship side West Brom at the London Stadium.
Barcelona slipped up at Valencia while Sevilla stay in third after beating Granada 2-0 at the Sanchez Pizjuan.
Slovenian Josip Illicic scored a treble in Atalanta's 7-0 demolition of nine-man Torino.
Marseille were held goalless by Angers to leave them well behind leaders PSG.
Erling Haaland produced another two goals as Dortmund overcame Cologne 5-1 at Signal Iduna Park on Friday night.
As the top of the Bundesliga tightens up following RB Leipzig's loss in Frankfurt and wins for Moenchengladbach and Bayern Munich (5-0 against Schalke)
Braga beat Porto 1-0 thanks to a Ricardo Horta winner to claim the Portuguese League Cup.
AFRICAN PLAYER NEWS & GOSSIP
Transfers - Moussa Kone (Senegal) to Nimes, Fakheredine Ben Youssef (Tunisia) to Ismaily, Yassin Ayoub (Morocco) to Panathinaikos, Benjamin Moukandjo (Cameroon) to Valenciennes, Aly Abeid (Mauritania) also to Valenciennes, Stephane Mbia (Cameroon) to Shanghai Shenhua, Bassem Srarfi (Tunisia) to Zulte Waregem.
Loan deals - Nabil Bentaleb (Algeria) to Newcastle, Walid Azaro (Morocco) to Al-Ettifaq in Saudi Arabia, Victor Moses (Nigeria) to Inter, Assan Ceesay (Gambia) to Osnabruck, Musa Barrow (Gambia) to Bologna, Oussama Haddadi (Tunisia) to Kasimpasa.