Hosts Ivory Coast completed a famous victory in the final after they fought back to beat Nigeria 2-1 at an ecstatic Alassane Ouatarra Stadium in Abidjan.
It was the Elephant's third title and certainly their most surprising following defeats in the group stage and the sacking of their original coach.
But ex-player Emerse Fae inspired an incredible turnaround culminating in a personal triumph for Sebastien Haller who struck the winner late in the second half.
The fifth round of group action saw six of the eight knockout places now confirmed with TP Mazembe, Mamelodi Sundowns, Petro de Luanda, Al Ahly, and Young Africans joining Ivorians ASEC Mimosas in the last eight.
And, in the final round, Esperance confirmed their place after edging Al Hillal 1-0 while Simba had few problems making it through with a 6-0 home victory.
Congratulations to Mamelodi Sundowns after they won the first-ever title by beating Wydad 2-0 in Pretoria.
Goals from Aubrey Modiba and Namibian Peter Shalulile secured the victory for Rulani Mukwena's team.
The Premier League's Manchester City and Arsenal are considered favourites to win the UCL (at Wembley) after they were drawn against Real Madrid and Bayern Munich respectively.
Atletico, who meet less-favoured Borussia Dortmund, and PSG, who face a tight contest with Barcelona, will battle for the other sem-final places.
Juregn Klopp's Liverpool are as restricted as even money to win the UEL, they meet Atalanta in the quarter-finals while West Ham have been matched with still unbeaten Bayer Leverkusen.
The other last eight encounters are Benfica v OM and an all-Italian matchup between AC Milan and Roma.
Unai Emery's Aston Villa go into the quarter-finals against Lille while Fiorentina clash with Plzen.
And there are potentially volatile meetings between the Turks of Fenerbahce and the Greeks of Olympiakos plus a visit to POAK for Club Brugge.
It remains a three-way battle for the EPL title after leaders Arsenal beat Brentford while the heavyweight clash between Liverpool and Manchester City ended even at Anfield.
Real Madrid, after winning 4-2 at Osasuna, moved ten clear of Girona (who lost at Getafe)
Simone Inzaghi's Inter continued their cruise to the Scudetto following their single-goal defeat of Bologna thanks to Yann Bisseck.
Though they were held at home by Reims PSG still stretched their advantage after second-placed Brest lost to Lens.
Still unbeaten Bayer Leverkusen have nine more games to complete a historic title victory, that was despite the champions Bayern Munich thumping Mainz 8-1 at the Arena.
The status quo was maintained in Portugal after Porto, Benfica, and leaders Sporting all scored three winning goals last weekend.